产品货号:
Z39077
中文名称:
XBP1抗体
英文名称:
Anti-XBP1 Antibody (Clone#3H1G4)
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-XBP1 Antibody (Clone#3H1G4) |
指标别名 | TREB5;X box binding protein 1;XBP 1;XBP1;XBP1s;XBP-1S;XBP1U;XBP2 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ICC,IF,ELISA |
基因名称 | XBP1 |
克隆号 | 3H1G4 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Mouse monoclonal XBP-1 antibody was raised against recombinant protein corresponding to amino acids 2 to 160 of human XBP-1. |
计算分子量 | 29kDa |
成分 | XBP-1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | XBP-1 Monoclonal Antibody is Protein A purified. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | XBP-1 monoclonal antibody can be stored at -20℃,stable for one year. |
背景资料 | X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER).Upon sensing unfolded proteins,an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA.The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes.Together with other UPR transcription factors such as ATF6,XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94. |
Uniprot ID | P17861 |
基因名全称 | X-box binding protein 1 |
蛋白名全称 | X-box binding protein 1 |
推荐稀释比 | XBP-1 antibody can be used for the detection of XBP-1 by Western blot at 1μg/mL.Antibody can also be used for immunocytochemistry starting at 2μg/mL.For immunofluorescence start at 4μg/mL.Antibody validated:Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
相关搜索:XBP1抗体,XBP1单抗,Anti-XBP1 Antibody (Clone#3H1G4)